When choosing which card to discard, take into account both what your opponents might use and what you need to finish your own melds. For instance, it is usually better to discard a low-value card that does not contribute to your melds than oacradene that might assist an opponent in finishing a set or run. ". You can keep control of the game by using this defensive strategy to keep your opponents from getting an advantage. Also, timing is very important when discarding. Depending on what has already been played, some cards may have different values as the game goes on. For example, it might be wise to discard a high-value card you are holding onto as soon as possible if it helps an opponent but does not fit into any melds.